rhinosinusitis predispose asthmatic patients to severe bronchial asthma
نویسندگان
چکیده
in this study, we evaluated the relationship between rhinosinusitis to the severity of asthma in asthmatic patients. this cross-sectional study was conducted on 90 patients with asthma referring to imam khomeini hospital in ardabil city. asthma control stepping method was used for staging of asthma severity. patients' clinical signs and paraclinical findings were individually evaluated and compared with particular attention to the presence or absence of rhinosinusitis. chi square and t-test were used to analyze the data in spss15 software. rhinosinusitis was found in 66 (73%) of the 90 patients. the forced expiratory volume in 1 second (fev1) was significantly lower in the patients who also had rhinosinusitis (p=0.002).comparing severity of asthma, most of the patients with rhinosinusitis were in stage3 (42.4%) but most of the patients without rhinosinusitis were in stage1 (41.6%) (p=0.002). the results of this study confirm the correlation between asthma severity and rhinosinusitis in asthmatic patients. therefore, in diagnosing asthma in patients, the possibility of the rhinosinusitis should be determined and treated.
منابع مشابه
Rhinosinusitis predispose asthmatic patients to severe bronchial asthma.
In this study, we evaluated the relationship between rhinosinusitis to the severity of asthma in asthmatic patients.This cross-sectional study was conducted on 90 patients with asthma referring to Imam Khomeini Hospital in Ardabil city. Asthma control stepping method was used for staging of asthma severity. Patients' clinical signs and paraclinical findings were individually evaluated and compa...
متن کاملImpact of chronic rhinosinusitis on severe asthma patients
Coexistence of chronic rhinosinusitis (CRS) with asthma appears to impair asthma control. Type-2 innate lymphoid cells (ILC2s) respond to the cytokines of thymic stromal lymphopoietin (TSLP), interleukin (IL)-25 and IL-33, thus contributing to airway diseases such as CRS and asthma. We investigate whether the augmented Th2-cytokines in CRS might be related to sinonasal tract ILC2s corresponding...
متن کاملThe role of rhinosinusitis in severe asthma
The prevalence of asthma is approximately 5% to 10% in the general population. Of these, approximately 5% to 10% are severe asthmatics who respond poorly to asthmatic drugs, including high-dose inhaled steroids. Severe asthmatics have persistent symptoms, frequent symptom exacerbation, and severe airway obstruction even when taking high-dose inhaled steroids. The medical costs of treating sever...
متن کاملBronchial angiogenesis in severe glucocorticoid-dependent asthma.
To examine the role of the bronchial microvasculature and adhesion molecule expression in severe asthma, the authors have performed an immunohistochemical study on bronchial biopsies comparing 15 glucocorticoid-dependent asthmatics, 15 mild asthmatics and eight control subjects. Serially cut glycol methacrylate-embedded sections were stained with monoclonal antibodies identifying the vessel mar...
متن کاملAcute severe alcohol-induced bronchial asthma.
We report the case of a severe bronchial asthma attack 15 minutes after the ingestion of food containing small amounts of alcohol. Although an ethanol inhalation test was negative, an acetaldehyde inhalation test was positive. Furthermore, it was discovered that the patient was homozygous for a mutation of the aldehyde dehydrogenase-2 (ALDH-2) gene. We subsequently diagnosed his attack as acute...
متن کاملBronchial thermoplasty: a novel therapeutic approach to severe asthma.
Bronchial thermoplasty is a non-drug procedure for severe persistent asthma that delivers thermal energy to the airway wall in a precisely controlled manner to reduce excessive airway smooth muscle. Reducing airway smooth muscle decreases the ability of the airways to constrict, thereby reducing the frequency of asthma attacks. Bronchial thermoplasty is delivered by the Alair System and is perf...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
iranian journal of allergy, asthma and immunologyجلد ۸، شماره ۴، صفحات ۱۹۹-۲۰۳
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023